Antibody-nanobody combination increases their neutralizing activity against sars-cov-2 and nanobody h11-h4 is effective against alpha, kappa and delta variants

HIGHLIGHTS

  • who: Hung Nguyen from the Institut have published the paper: Antibody-nanobody combination increases their neutralizing activity against SARS-CoV-2 and nanobody H11-H4 is effective against Alpha, Kappa and Delta variants, in the Journal: Scientific Reports Scientific Reports
  • what: As shown in previous u00adworks26,55, this approach provides reasonable results on the relative binding affinity of protein-protein complexes.

SUMMARY

    From Eq, the authors can extract the equilibrium free_energy if the number of SMD trajectories is large enough and the pulling is sufficiently slow. Binding free_energy of H11‑H4 . . .

     

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