Development of a chemoresistant risk scoring model for prechemotherapy osteosarcoma using single-cell sequencing

HIGHLIGHTS

  • who: Ziliang Zeng from the University of Alabama at Birmingham, United States have published the research work: Development of a Chemoresistant Risk Scoring Model for Prechemotherapy Osteosarcoma Using Single-Cell Sequencing, in the Journal: (JOURNAL)
  • what: The authors focused on 2 aspects of the tumor environment surrounding chemoresistant tumor cells. Based on bulk RNA results, the authors focused on osteoblastic lineage expression, including cell proliferation, extracellular matrix (ECM) secretion, and ossification induction among tumor cells . The authors aimed to reveal chemoresistance-related expression profiles and establish a chemoresistance risk score model for osteosarcoma patients based . . .

     

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