HIGHLIGHTS
- who: Frederik Denorme et al. from the Department University of Utah, Salt Lake City, Utah, USA have published the paper: Neutrophil extracellular traps regulate ischemic stroke brain injury Molecular Medicine Program 2Department, in the Journal: (JOURNAL)
- what: The authors investigated mechanistic regulators of neutrophil extracellular trap (NET) formation in stroke and whether they contribute to stroke outcomes. Through a translational approach studying ischemic stroke patients and employing murine models of ischemic stroke, the authors report a key role for platelet-derived high-mobility group box 1 (HMGB1) in the formation of NETs in the acute . . .
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