Bempedoic acid restores liver h2s production in a female sprague-dawley rat dietary model of non-alcoholic fatty liver

HIGHLIGHTS

  • who: Nu00faria Roglans and collaborators from the Department of Pharmacology, Toxicology and Therapeutic Chemistry, School of Pharmacy and Food Science, University of Barcelona, AvJoan XXIII, Barcelona, Spain have published the research: Bempedoic Acid Restores Liver H2S Production in a Female Sprague-Dawley Rat Dietary Model of Non-Alcoholic Fatty Liver, in the Journal: (JOURNAL)
  • what: Using this model, the authors recently demonstrated that BemA administration strongly reverses hepatic triglyceride deposition . The authors provide possible molecular mechanisms responsible for these changes, involving FXR, PGC-1u03b1 (peroxisome proliferator receptor gamma coactivator-1u03b1), and mTORC1 (mammalian target of . . .

     

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