Exploring the mechanism of adjuvant treatment of glioblastoma using temozolomide and metformin

HIGHLIGHTS

  • who: Shao-Wei Feng et al. from the Department of Neurologic Surgery, Tri-Service General Hospital, National Defense Medical Center, Department of Biochemistry, National Defense Medical Center, Taipei, Taiwan have published the article: Exploring the Mechanism of Adjuvant Treatment of Glioblastoma Using Temozolomide and Metformin, in the Journal: (JOURNAL) of 15/01/2021
  • what: The aim of this study is to investigate the mechanism of metformin as a potential adjuvant treatment drug in glioblastoma. The study showed that metformin decreased metabolic activity proliferation migration mitochondrial biogenesis and mitochondrial membrane potential and increased apoptosis and ROS . . .

     

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