Phosphoinositol 3-kinase-driven net formation involves different isoforms and signaling partners depending on the stimulus

HIGHLIGHTS

• who: Vanessa de Carvalho Oliveira and colleagues from the University of Verona, Italy have published the research work: Phosphoinositol 3-kinase-driven NET formation involves different isoforms and signaling partners depending on the stimulus, in the Journal: (JOURNAL)
• what: The inhibitors were added either before or after stimulation; the authors focused on PI3Ka and PI3Kg isoforms because they yielded the greatest inhibition and were mobilized by all stimuli tested. And in agreement with the previous finding that PI3K affects NET generation belatedly , the authors show that all PI3K-related Frontiers in Immunology frontiersin.org 10 . . .
  

   

  

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