Metformin promotes mechanical stretch-induced skin regeneration by improving the proliferative activity of skin-derived stem cells

HIGHLIGHTS

  • who: Zhou Yu and Xianjie Ma from the Military Medical University (Xiu2019an, China)Twenty were have published the research work: Metformin Promotes Mechanical Stretch-Induced Skin Regeneration by Improving the Proliferative Activity of Skin-Derived Stem Cells, in the Journal: (JOURNAL)
  • what: The authors investigated the ability of metformin to promote regeneration of mechanically stretched skin. The authors provided direct evidence that the topical application of metformin could promote the proliferation of ESCs and HFBSCs using IHC staining, doubleimmunofluorescence staining, and measurement of protein expression levels.
  • how: After measuring and collecting blood-flow . . .

     

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