The common cellular events in the neurodegenerative diseases and the associated role of endoplasmic reticulum stress

HIGHLIGHTS

  • who: Soojeong Kim and colleagues from the Department of New Biology, Gyeongbuk Institute of Science and Technology (DGIST) have published the article: The Common Cellular Events in the Neurodegenerative Diseases and the Associated Role of Endoplasmic Reticulum Stress, in the Journal: (JOURNAL) of 20/05/2022

SUMMARY

    The ER also plays a role in protein quality_control, a defense 2 of 33 mechanism that prevents misfolded proteins from aggregating. In many neurodegenerative diseases, ER stress and the presence of inclusion bodies composed of misfolded protein aggregates are observed early in the symptomatic stage, implying . . .

     

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