Monocarboxylate transporter 1 deficiency impacts cd8+ t lymphocytes proliferation and recruitment to adipose tissue during obesity

HIGHLIGHTS

  • who: C. Macchi from the of Pharmacological and Biomolecular Sciences, Universitau0300 degli Studi di Milano, Milan, Italy have published the article: Monocarboxylate transporter 1 deficiency impacts CD8+ T lymphocytes proliferation and recruitment to adipose tissue during obesity, in the Journal: (JOURNAL) of June/17,/2022
  • what: On these premises, the authors aimed at characterizing the role of MCT1 selective deficiency in lymphocyte T_cells in modulating T_cell effector response during a state of low-grade inflammation. This study shows that MCT1 transporter deficiency affects metabolic reprogramming of activated CD8+ T_cells and their recruitment in adipose_tissue during . . .

     

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