Imaging the response to dna damage in heterochromatin domains

HIGHLIGHTS

  • who: DNA damage and collaborators from the Epigenetics and Cell Fate Centre, CNRS, Universitu00e9 Paris Citu00e9, Paris, France Michigan State University have published the article: Imaging the Response to DNA Damage in Heterochromatin Domains, in the Journal: (JOURNAL)
  • what: The authors assess the DDR in these heterochromatin domains after induction of two types of DNA damage: UVC-induced photolesions and DSBs. The authors describe how to generate photolesions in pericentric heterochromatin by targeting a UVC laser to chromocenters .

SUMMARY

    Constitutive heterochromatin is highly conserved across different cell types and is tightly . . .

     

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