HIGHLIGHTS
- who: Henning Tim Langer from the University of Texas Southwestern Medical Center, United States have published the research: Systemic Ketone Replacement Does Not Improve Survival or Cancer Cachexia in Mice With Lung Cancer, in the Journal: (JOURNAL)
- what: To investigate whether PPARa activity plays a pathophysiologic role in cancer cachexia in this model, the authors examined PPARa activity in the liver of mice fed normal chow and the ketone ester diet.
- how: To test this hypothesis the authors conducted two prospective randomized nutritional intervention trials that directly and indirectly increased ketone body availability . . .
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