Engineering of src homology 2 domain leading to sulfotyrosine recognition with a high affinity by integrating a distinctive selection theme and next-generation sequencing

HIGHLIGHTS

• who: Yunkun Qi and Lei Li from the University of Electronic Science and of China, China have published the Article: Engineering of Src Homology 2 Domain Leading to Sulfotyrosine Recognition With a High Affinity by Integrating a Distinctive Selection Theme and Next-Generation Sequencing, in the Journal: (JOURNAL)
• how: Biopanning This study used two modified peptides to identify sY superbinders for biopanning sY peptide and pY counterpart. sY peptide was used to discover sY superbinders from SH2 domain-based phage libraries (Ju et_al 2016 Lawrie et_al 2021). In this study the variant SH2-4 was . . .
  

   

  

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