HIGHLIGHTS
- who: Bao Ying Liu et al. from the Hong Kong Polytechnic University, Hong Kong SAR, China have published the paper: Epididymal epithelial degeneration and lipid metabolism impairment account for male infertility in occludin knockout mice, in the Journal: (JOURNAL)
- what: This study investigated the role of OCLN in sperm maturation in epididymis by determining its role in luminal microenvironment homeostatic regulation. This study shows that tight-junction OCLN, located at the apical junction membrane of principal cells of proximal epididymis, is involved in ensuring epididymal integrity, acid secretion, and cellular metabolism, thereby ensuring male fertility . . .
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