Human milk oligosaccharide 2`-fucosyllactose inhibits ligand binding to c-type lectin dc-sign but not to langerin

HIGHLIGHTS

• who: Reshmi Mukherjee et al. from the Division of Pharmacology, Utrecht Institute of Pharmaceutical Sciences, Faculty of Science, Utrecht University, Universiteitsweg, TB Utrecht, The Netherlands have published the research: Human Milk Oligosaccharide 2`-Fucosyllactose Inhibits Ligand Binding to C-Type Lectin DC-SIGN but Not to Langerin, in the Journal: (JOURNAL)
• what: The authors show using a ligand-receptor competition assay that a whole mixture of HMOs from pooled human milk (HMOS) and 20 -FL inhibit the binding of the carbohydrate-binding receptor DC-SIGN to its prototypical ligands fucose and the Lewis-B (Leb . . .
  

   

  

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