The nox2-ros-nlrp3 inflammasome signaling stimulates in the hematopoietic stem/progenitor cells lipogenesis to facilitate membrane lipid raft formation

HIGHLIGHTS

  • who: Ahmed Abdelbaset-Ismail from the Laboratory of Regenerative Medicine, Medical University of Warsaw, Warsaw, Poland have published the research: The Nox2-ROS-Nlrp3 Inflammasome Signaling Stimulates in the Hematopoietic Stem/Progenitor Cells Lipogenesis to Facilitate Membrane Lipid Raft Formation, in the Journal: (JOURNAL)
  • what: Based on the previous research showing that HSPCs from Nox2-KO and Nlrp3-KO mice display a profound defect in MLRs the authors focused on role of in regulating lipogenesis in HSPCs. The authors provide novel evidence that Nox2-derived ROS are required for a proper expression of enzymes regulating . . .

     

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