HIGHLIGHTS
- who: Iga Kucharska and colleagues from the Editor: KHiggins, University of Oxford, of Immunology, University of Toronto, Toronto, Ontario, Canada have published the research: High-density binding to Plasmodium falciparum circumsporozoite protein repeats by inhibitory antibody elicited in mouse with human immunoglobulin repertoire, in the Journal: (JOURNAL) of November/28,/2022
- what: The authors characterize IGHV3-33/IGKV1-5-encoded monoclonal antibody (mAb) 850 elicited by immunization of transgenic mice with human immunoglobulin loci. mAb 850 binds repeating NANP motifs with picomolar affinity potently inhibits Plasmodium falciparum (Pf) in vitro and when passively administered in . . .
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