Relating protein crystal structure to ligand-binding thermodynamics

HIGHLIGHTS

  • who: John R. Helliwell from the Department of Chemistry, University of Manchester, Manchester , PL, United Kingdom* have published the article: Relating protein crystal structure to ligand-binding thermodynamics, in the Journal: (JOURNAL) of 19/Oct/2022

SUMMARY

    An important interface between biophysical chemistry and biological crystal_structures involves whether it is possible to relate experimental calorimetry measurements of protein ligand binding to 3D structures. The impetus for writing this update now, as a Scientific Comment, is that a breakthrough in neutron crystal_structure determinations of saccharidebound lectins has been achieved. To secure this link, molecular . . .

     

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