Piezo1 channels in cutaneous free nerve endings: novel insights into itch-scratch-mechanisms

HIGHLIGHTS

  • who: Manuel Pedro Pereira from the DepartmentUniversity Hospital Mu00fcnster, Mu00fcnster, Germany have published the research work: PIEZO1 channels in cutaneous free nerve endings: novel insights into itch-scratch-mechanisms, in the Journal: (JOURNAL) of 29/07/2022

SUMMARY

    Received PIEZO1 channels in cutaneous free nerve endings: novel insights into... Pereira et_al after intraperitoneal injection of the toxin GsMTx4 reduced mechanically evoked scratching in naive mice. Based on these experiments, the authors conclude that subsets of peripheral slow conduction C-fibers expressing PIEZO1 promote itch and alloknesis upon mechanical stimulation. These nerve fibers are . . .

     

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