The rs368698783 (g>a) polymorphism affecting lyar binding to the a-globin gene is associated with high fetal hemoglobin (hbf) in -thalassemia erythroid precursor cells treated with hbf inducers

HIGHLIGHTS

  • who: Cristina Zuccato and colleagues from the University of Ferrara, Ferrara, Italy have published the paper: The rs368698783 (G>A) Polymorphism Affecting LYAR Binding to the A-Globin Gene Is Associated with High Fetal Hemoglobin (HbF) in -Thalassemia Erythroid Precursor Cells Treated with HbF Inducers, in the Journal: (JOURNAL) of 14/Nov/2018
  • what: The aim of this study was to stratify patients with respect to the rs368698783 (G>A) and to verify whether their cells (ErPCs) differentially respond in vitro to selected fetal hemoglobin (HbF) inducers. Of this trial have been reported recently . mRNA . . .

     

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