HIGHLIGHTS
- who: . and colleagues from the Harbin Medical University, China have published the Article: The role of metabolic reprogramming in pancreatic cancer chemoresistance, in the Journal: (JOURNAL)
- what: In this review, the authors focused on the molecular mechanisms and latest advances of metabolic reprogramming affecting PC chemoresistance, considered the role of the mitochondria, and suggested new approaches to overcoming chemoresistance.
SUMMARY
Both GLUT1 and SLC2A1, which encode GLUT-1 protein, are highly expressed in PC cells and are associated with poor clinical prognosis (Yu et_al, 2017; Kurahara et_al, 2018; Du et_al, 2021 . . .
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