Cinobufagin alleviates lipopolysaccharide-induced acute lung injury by regulating autophagy through activation of the p53/mtor pathway

HIGHLIGHTS

  • who: November and collaborators from the Tianjin Medical University, China have published the paper: Cinobufagin alleviates lipopolysaccharide-induced acute lung injury by regulating autophagy through activation of the p53/mTOR pathway, in the Journal: (JOURNAL)
  • what: The aim of this study was to clarify whether cinobufagin exerts anti-inflammatory effects in LPSinduced ALI. The study showed that cinobufagin activates autophagy in LPS-induced ALI.
  • how: Indicated that 3-MA (2 u03bcM) Frontiers in Pharmacology frontiersin.org 10.3389/fphar.2022.994625 These results indicated that cinobufagin could induce autophagy in ALI in_vitro. With . . .

     

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