In silico investigation of the human gtp cyclohydrolase 1 enzyme reveals the potential of drug repurposing approaches towards the discovery of effective bh4 therapeutics

HIGHLIGHTS

• who: Dania Hussein from the Department of Pharmacology and Toxicology, College of Clinical Pharmacy, Imam Abdulrahman bin Faisal have published the Article: In Silico Investigation of the Human GTP Cyclohydrolase 1 Enzyme Reveals the Potential of Drug Repurposing Approaches towards the Discovery of Effective BH4 Therapeutics, in the Journal: (JOURNAL) of 23/Dec/2022
• what: Targeting the BH4 biosynthetic pathway holds great therapeutic potential for a number of diseases.
• how: The authors identified a number of drugs that bind to the GTPCH1 active_site using molecular modeling platforms. The authors utilized an in silico . . .
  

   

  

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