Autologous t cell therapy for mage-a4+ solid cancers in hla-a*02+ patients: a phase 1 trial

HIGHLIGHTS

  • who: David S. Hong from the (UNIVERSITY) have published the research: Autologous T cell therapy for MAGE-A4+ solid cancers in HLA-A*02+ patients: a phase 1 trial, in the Journal: (JOURNAL) of 30/Dec/2019
  • how: The authors conducted a multicenter dose-escalation phase 1 trial in patients with relapsed/refractory metastatic solid tumors expressing MAGE-A4 including synovial sarcoma (SS) ovarian cancer and head and neck cancer (NCT03132922). In this phase 1 trial the authors evaluated the safety clinical activity and translational effects of afami-cel in HLA-A*02+ patients with . . .

     

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