Proteomics and weighted gene correlated network analysis reveal glutamatergic synapse signaling in diazepam treatment of alcohol withdrawal

HIGHLIGHTS

  • who: . and colleagues from the Shanghai Jiao Tong University, China have published the paper: Proteomics and weighted gene correlated network analysis reveal glutamatergic synapse signaling in diazepam treatment of alcohol withdrawal, in the Journal: (JOURNAL)
  • what: The research showed that Glutamatergic synapses may be a potential molecular target for new interventional strategies. The authors propose that reduced CaMKII expression or activity may be considered as a protective mechanism to resist abnormal synaptic potentiation during ethanol deprivation. This study showed that ethanol withdrawal increased EAAT4 (Slc1a6) expression, which was the largest change among DEPs compared with . . .

     

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