Elucidating the molecular determinants in the process of gastrin c-terminal pentapeptide amide end activating cholecystokinin 2 receptor by gaussian accelerated molecular dynamics simulations

HIGHLIGHTS

• who: . and colleagues from the University of Kansas, United States have published the article: Elucidating the molecular determinants in the process of gastrin C-terminal pentapeptide amide end activating cholecystokinin 2 receptor by Gaussian accelerated molecular dynamics simulations, in the Journal: (JOURNAL)
• what: The authors performed extensive GaMD simulations to investigate the molecular determinants in the process of gastrin C-terminal pentapeptide amide end activating CCK2R.

SUMMARY

Point mutations also found some residues in CCK2R can significantly alter the activity of gastrin and CCK(Silvente-Poirot et_al, 1998; Anders et_al, 1999 . . .

 



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