HIGHLIGHTS
- who: Rui Gao from the (UNIVERSITY) have published the research: Resetting histone modifications during human prenatal germline development, in the Journal: (JOURNAL)
- what: By applying ultralow-input micrococcal nucleasebased native chromatin immunoprecipitation followed by sequencing (ULI-NChIP-seq) analysis, the authors provide highresolution, genome-wide, comprehensive chromatin data for both male and female fetal hPGCs as well as gonadal somatic_cells for the first time during 16 weeks of development, from Wk8 to Wk23 of gestation. The authors demonstrate that H3K4me3 exhibits a canonical promoter-enriched pattern, and shows a high correlation with transcription. The authors . . .
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