Microglia remodelling and neuroinflammation parallel neuronal hyperactivation following acute organophosphate poisoning

HIGHLIGHTS

  • who: Julie Somkhit et al. from the (UNIVERSITY) have published the research work: Microglia Remodelling and Neuroinflammation Parallel Neuronal Hyperactivation Following Acute Organophosphate Poisoning, in the Journal: (JOURNAL) of 11/07/2022
  • how: Showed that microglial cells could be clustered into three distinct populations in controls . The authors used pU.1 morphants neuronal hyperexcitation and epileptogenesis . The results indicated that fosab RNAs were still overexpressed in pU.1 morphants exposed to DFP albeit at significantly reduced levels when compared to that observed in their wild-type counterparts (fc 7.3 u00b1 1.5 vs. 22 . . .

     

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