HIGHLIGHTS
- who: Kenichiro Motomura and collaborators from the Division State University of Medicine, Detroit, Michigan, USA have published the paper: Fetal and maternal NLRP3 signaling is, in the Journal: (JOURNAL) of July/18,/2022
- what: The authors report that the intra-amniotic administration of LPS to Nlrp3-deficient mice triggered an inflammatory milieu in the fetal membranes similar to that observed in WT mice; however, the processing of mature IL-1u03b2 was defective as a consequence of impaired CASP-1 activation. In the study herein, the authors provide the first evidence to the knowledge that NLRP3 . . .
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