Synthesis of novel 1,3,4-oxadiazole-derived -aminophosphonates/-aminophosphonic acids and evaluation of their in vitro antiviral activity against the avian coronavirus infectious bronchitis virus

HIGHLIGHTS

  • who: Shaima Hkiri and colleagues from the Synthu00e8se Organomu00e9tallique et Catalyse, UMR-CNRS, University of Strasbourg, rue Blaise Pascal, Strasbourg, France have published the article: Synthesis of Novel 1,3,4-Oxadiazole-Derived -Aminophosphonates/-Aminophosphonic Acids and Evaluation of Their In Vitro Antiviral Activity against the Avian Coronavirus Infectious Bronchitis Virus, in the Journal: Pharmaceutics 2023, 114 of /2023/
  • what: The authors also examined the interactions of 5f and 6a with the N- and C-terminal domains of coronavirus nucleocapsid protein.
  • how: A selection of the synthesized compounds was tested for their 3 . . .

     

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