HIGHLIGHTS
- who: Haihong Jin from the Medicinal Chemistry Core, Oregon Health and Science University have published the Article: Deaza-modification of MR1 ligands modulates recognition by MR1-restricted T cells, in the Journal: Scientific Reports Scientific Reports
SUMMARY
The authors prepared 2′-deoxy-DZ (dDZ) (Fig 1d), lacking the 2′-hydroxyl of the ribityl moiety, and a deaza-version of photolumazine I (DZPLI, Fig 1e), a novel MR1T_cell-activating ribityllumazine ligand the authors recently described13. To determine whether or not DZ is a MR1T_cell antigen, the authors tested the synthetic DZ molecule, alongside DMRL . . .
If you want to have access to all the content you need to log in!
Thanks :)
If you don't have an account, you can create one here.