Delivery and assessment of a crispr/ncas9-based genome editing system on in vitro models of mucopolysaccharidoses iva assisted by magnetite-based nanoparticles

HIGHLIGHTS

  • who: Andru00e9s Felipe Leal from the Institut of Science, Pontificia Universidad Javeriana have published the article: Delivery and assessment of a CRISPR/nCas9-based genome editing system on in vitro models of mucopolysaccharidoses IVA assisted by magnetite-based nanoparticles, in the Journal: Scientific Reports Scientific Reports
  • what: In this study, we have expanded our previous findings related to the potential use of a CRISPR/nCas9-based genome edition system to four in_vitro models of MPS IVA containing different mutations using a non-viral_vector based on MLPs for the delivery of the CRISPR/nCas9 system.
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