The biological and clinical consequences of rna splicing factor u2af1 mutation in myeloid malignancies

HIGHLIGHTS

• who: Yangjing Zhao and colleagues from the Jiangsu Key Laboratory of Medical Science and Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, China have published the research work: The Biological and Clinical Consequences of RNA Splicing Factor U2AF1 Mutation in Myeloid Malignancies, in the Journal: Cancers 2022, 4406 of /2022/
• what: There are four studies reporting that the presence of U2AF1 mutations has no significant impact on the overall survival (OS) or leukemia-free survival in MDS patients .
• future: Future research should explore the exact molecular mechanisms of U2AF1 mutations in driving leukemogenesis . . .
  

   

  

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