Rcan1 knockout and overexpression recapitulate an ensemble of rest-activity and circadian disruptions characteristic of down syndrome, alzheimer’s disease, and normative aging

HIGHLIGHTS

  • who: Helen Wong from the Institute for Behavioral Genetics, University of Colorado Boulder, , th Street, Boulder, CO, u20110447, USA have published the article: RCAN1 knockout and overexpression recapitulate an ensemble of rest-activity and circadian disruptions characteristic of Down syndrome, Alzheimeru2019s disease, and normative aging, in the Journal: (JOURNAL)
  • what: This study examined the impacts of deficiency and overexpression on the photic entrainment circadian periodicity intensity and distribution diurnal patterning and circadian rhythmicity of wheel running in young (3-6 months old) and aged (9-14 months old) mice of both sexes. This study characterizes . . .

     

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