Loss of atrx promotes aggressive features of osteosarcoma with increased nf-κb signaling and integrin binding

HIGHLIGHTS

• who: Suzanne Bartholf DeWitt and colleagues from the DepartmentDuke University of Texas at San Antonio, San Antonio, Texas, USA have published the paper: Loss of ATRX promotes aggressive features of osteosarcoma with increased NF-u03baB signaling and integrin binding, in the Journal: (JOURNAL) of May/20,/2021
• what: The authors show that decreased ATRX expression is associated with more aggressive tumor cell phenotypes including increased growth migration invasion and metastasis. The authors characterize these changes in vitro in vivo and in a data set of human OS patients. The research has not completely elucidated how . . .
  

   

  

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