HIGHLIGHTS
- who: Tasneem Elamin from the (UNIVERSITY) have published the Article: Structural and functional studies of legumain-mycocypin complexes revealed a competitive, exosite-regulated mode of interaction, in the Journal: (JOURNAL) of September/10,/2022
- what: The authors show that mycocypins utilize an adaptable reactive center loop to target the active_site of legumain in a substrate-like manner. The models showed that the prime side EX1Mcp interaction mediated by Arg96Mcp on Mcp1a was not possible in the investigated plant legumains, since the corresponding interaction partner Asp160 on human legumain is replaced by His182 in AtLEGu03b2 and . . .
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