Cytochrome p450 1b1: a key regulator of ocular iron homeostasis and oxidative stress

HIGHLIGHTS

  • who: Yong-Seok Song et al. from the Departments of Ophthalmology and Visual Sciences, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA have published the article: Cytochrome P450 1B1: A Key Regulator of Ocular Iron Homeostasis and Oxidative Stress, in the Journal: Cells 2022, 2930 of 15/08/2022
  • what: The authors propose that CYP1B1 expression in the retinal endothelium may contribute to the processes involved in local iron homeostasis. The authors propose the decreased hepcidin in the liver of Cyp1b1-/- 12 of 21 mice leads to increased systemic iron . . .

     

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