Ligand-receptor promiscuity enables cellular addressing

HIGHLIGHTS

• who: Christina J. Su from the Division of Technology, Pasadena, CA, USA University of have published the research work: Ligand-receptor promiscuity enables cellular addressing, in the Journal: (JOURNAL) of May/18,/2022
• what: The authors focus on this third class of mechanism. Briefly, the model describes a set of nL ligands, nA type I receptors, and nB type II receptors.
• how: To investigate this issue the authors developed a general mathematical modeling framework based on the bone morphogenetic protein (BMP) pathway architecture. In well-studied systems individual cells co-express multiple receptor . . .
  

   

  

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