Human milk oligosaccharide 2`-fucosyllactose promotes melanin degradation via the autophagic ampk-ulk1 signaling axis

HIGHLIGHTS

• who: Hyojin Heo from the DepartmentAjou University have published the research work: Human milk oligosaccharide 2`-fucosyllactose promotes melanin degradation via the autophagic AMPK-ULK1 signaling axis, in the Journal: Scientific Reports Scientific Reports
• what: This study shows that 2`-FL reduces melanin levels in B16 murine cells, in a human skin equivalent in_vitro model, and in a mouse model. Although previous su00ad tudies48,49 demonstrated that LC3 can participate in melanogenesis by upregulating MITF, the study showed that expression levels of the melanogenic genes were not significantly changed (Supplementary Fig S1), suggesting that LC3 . . .
  

   

  

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