A yap/taz-tead signalling module links endothelial nutrient acquisition to angiogenic growth

HIGHLIGHTS

  • who: Yu Ting Ong from the Max Planck Institute for Heart and Lung Research, Bad Nauheim, GermanyUniversity of have published the Article: A YAP/TAZ-TEAD signalling module links endothelial nutrient acquisition to angiogenic growth, in the Journal: (JOURNAL) of 18/02/2021
  • what: The authors demonstrate that form transcriptional with TEADs to orchestrate the expression of cluster of cell-surface transporters importing amino acids and other metabolic fuels. by this supplies with resources for growth and proliferation and enables mTORC1 pathway activation thereby promoting anabolic processes such as protein and DNA synthesis.
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