Targeted and cellular therapies in lymphoma: mechanisms of escape and innovative strategies

HIGHLIGHTS

  • who: Anagha Deshpande from the Institute of Hematology and Transfusiology (IHT), Poland Wake Forest University, United States have published the article: Targeted and cellular therapies in lymphoma: Mechanisms of escape and innovative strategies, in the Journal: (JOURNAL)
  • what: This trial compared polatuzumab vedotin to pinatuzumab vedotin - another antibody-drug conjugate targeted at CD22 .
  • how: This study also found that cells became re-sensitized to treatment when an IGF1R inhibitor was utilized .
  • future: The authors of this study did note that further investigation of this mechanism of resistance is needed .
 

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