Comparative evaluation of inducible cre mouse models for fibroblast targeting in the healthy and infarcted myocardium

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  • who: Laura Pilar Aguado-Alvaro et al. from the Regenerative Medicine Department, Center for Applied Medical Research (CIMA)-Universidad de Navarra, Pamplona, Spain have published the paper: Comparative Evaluation of Inducible Cre Mouse Models for Fibroblast Targeting in the Healthy and Infarcted Myocardium, in the Journal: Biomedicines 2022, 2350 of 21/09/2022
  • what: The authors demonstrate optimal Cre recombinase activity in CF (but also although moderate in endothelial cells (ECs)) derived from healthy and infarcted hearts in the PDGFRa-creERT2 mouse strain. Cardiovascular diseases are the leading cause of morbidity and mortality worldwide, with . . .

     

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