Topography-induced large-scale antiparallel collective migration in vascular endothelium

HIGHLIGHTS

  • who: Claire Leclech from the CNRS de Lorraine, LCP-A MC, Metz, France have published the paper: Topography-induced large-scale antiparallel collective migration in vascular endothelium, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
  • what: The authors show that unconfined endothelial monolayers on microgrooves exhibit a specific type of collective migration that takes the form of periodic antiparallel cell streams whose characteristic dimensions are considerably larger than either the groove or cell size, suggesting that these topographic constraints induce long-range effects. The authors demonstrate that the streams develop in a monolayer that exhibits minimal . . .

     

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