A regulatory loop involving mir-200c and nf-b modulates mortalin expression and increases cisplatin sensitivity in an ovarian cancer cell line model

HIGHLIGHTS

• who: Xin Huang and colleagues from the Department of Cellular and Genetic Medicine, School of Basic Medical Sciences, Fudan University, Shanghai, China have published the research: A Regulatory Loop Involving miR-200c and NF-B Modulates Mortalin Expression and Increases Cisplatin Sensitivity in an Ovarian Cancer Cell Line Model, in the Journal: (JOURNAL) of 22/08/2022
• what: The authors uncovered a novel regulatory mechanism of mortalin mediated by miR-200b/c and NF-u03baB, and determined its effects on ovarian cancer. miR-200c treatment decreased mortalin expression and suppressed ovarian cancer malignancy . The study . . .
  

   

  

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