3′nucleotidase/nuclease is required for leishmania infantum clinical isolate susceptibility to miltefosine

HIGHLIGHTS

  • who: Juliana B.T. Carnielli from the York Biomedical Research Institute, Department of Biology, University of York, United Kingdom have published the Article: 3u2032Nucleotidase/nuclease is required for Leishmania infantum clinical isolate susceptibility to miltefosine, in the Journal: (JOURNAL)
  • what: Implications of all the available evidence the study showed that 3u2032 -nucleotidase/nucleases are the key components of the prognostic marker MSL involved in miltefosine susceptibility. The MSL, highlighted as a promising molecular marker to guide an accurate clinical practice approach, was the focus of this study aimed to investigate the underlying molecular resistance mechanisms . . .

     

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