Novel 1,2,3-triazole erlotinib derivatives as potent ido1 inhibitors: design, drug-target interactions prediction, synthesis, biological evaluation, molecular docking and adme properties studies

HIGHLIGHTS

• who: Derivatives as Potent I et al. from the Tianjin University, China have published the research work: Novel 1,2,3-Triazole Erlotinib Derivatives as Potent IDO1 Inhibitors: Design, Drug-Target Interactions Prediction, Synthesis, Biological Evaluation, Molecular Docking and ADME Properties Studies, in the Journal: (JOURNAL)
• what: In this study, a series of erlotinib derivatives containing 1,2,3triazole rings were designed through a structure-based method, combined with deep learning drug-target interaction models to predict affinities.
• how: The authors used the Mean Square Error (MSE) Concordance Index and Pearson Correlation as . . .
  

   

  

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