Transcriptome and proteome profiling of activated cardiac fibroblasts supports target prioritization in cardiac fibrosis

HIGHLIGHTS

  • who: Maria Raquel Moita from the University Hospital Erlangen, Germany have published the research work: Transcriptome and proteome profiling of activated cardiac fibroblasts supports target prioritization in cardiac fibrosis, in the Journal: (JOURNAL)
  • what: Thereby the authors provide a panel of putative novel targets for cardiac fibrosis. The authors demonstrate that hiPSC-CF is a suitable and sustainable cell source for in_vitro drug discovery displaying a significantly lower basal activation level as compared with primary cells, while retaining the ability to elicit a convergent response relative to primary cells upon stimuli. The aim of this . . .

     

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