Comparison of the immunomodulatory potential of platinum-based anti-cancer drugs and anthracyclins on human monocyte-derived cells

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  • who: Viktu00f3ria Jenei from the Department of Immunology, Faculty of Medicine, University of Debrecen, Egyetem Square, Debrecen, Hungary have published the research: Comparison of the immunomodulatory potential of platinum-based anti-cancer drugs and anthracyclins on human monocyte-derived cells, in the Journal: (JOURNAL)
  • what: The authors investigated two platinum-based antineoplastic agents; oxaliplatin and cisplatin, with the ability to crosslink with the urine bases on the DNA leading to DNA damage and subsequently apoptosis within cancer cells and two anthracyclines; doxorubicin and epirubicin with DNA intercalation ability and consequently inhibition of nucleic_acid and protein . . .

     

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