Influence of circadian clocks on adaptive immunity and vaccination responses

HIGHLIGHTS

• who: Louise Madeleine Ince from the Vaccination Commercial hepatitis A vaccine (HAVRIX, GlaxoSmithKline) was obtained via the clinic at the University Hospitals of Geneva (HUG)Mice were anesthetized with isoflurane inhalation and , u00b5l of the proprietary vaccine formula was injected into the thigh muscle. As an adjuvant control, u00b5l of Alhydrogel adjuvant, % diluted, :, in PBS was given to provide the equivalent alum content. A SARS-Co, vaccine was formulated in house using recombinant spike receptor binding domain (RBD) protein (aa319-591, kindly provided by the protein production core facility of the Ecole Polytechnique Fu00e9du00e9rale de Lausanne (EPFL . . .
  

   

  

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