Poly(i:c)-exposed zebrafish shows autism-like behaviors which are ameliorated by fabp2 gene knockout

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  • who: ufeffJingufeff ufeffWuufeff from the West Virginia University, United States have published the research: Poly(I:C)-exposed zebrafish shows autism-like behaviors which are ameliorated by ufefffabp2ufeff gene knockout, in the Journal: (JOURNAL) of 05/01/2023
  • what: The authors hypothesize that fabp2 may influence the immune microenvironment by regulating immune cells and immune-related pathways inducing an ASD behavior as observed in this study that fabp2 -/- larvae showed an impaired sociability. The authors established an environmental risk factor-ASD model in zebrafish and demonstrated its social behavior impairments that mimic human ASD phenotypes . . .

     

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