Eugenol induces apoptosis in tongue squamous carcinoma cells by mediating the expression of bcl-2 family

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SUMMARY

    Because of its frequent usage and due to the problem oral cancer poses today, this study was conducted to evaluate the in_vitro cytotoxicity of Eug on squamous cell tongue carcinoma. The following cell lines were used in this study: human gingival fibroblasts-HGF (PCS-201-018™) and squamous cell carcinoma cell line-SCC-4 (CRL-1624™), both purchased from ATCC. Similar results were obtained by Júnior P. and colleagues who have stimulated two breast cancer cell lines (MCF-7, MDA-MB-231), a cervix cancer cell line (SIHA), and two melanoma cell lines . . .

     

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